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A good nights sleep

If you are trying to have a baby, a good night's sleep is more important than ever. It is becoming increasingly apparent that the womb has its own "body clock” and that it needs to synchronise with the mother's body clock to ensure the best conditions for fetal growth and development. Any inability of a mother's body clock to synchronise with the womb's clock may be at least part of the reason why some women have difficulty carrying a pregnancy to full term.



If you are trying to have a baby, a good night's sleep is more important than ever. It is becoming increasingly apparent that the womb has its own "body clock” and that it needs to synchronise with the mother's body clock to ensure the best conditions for fetal growth and development. Any inability of a mother's body clock to synchronise with the womb's clock may be at least part of the reason why some women have difficulty carrying a pregnancy to full term.

It is important to sync your body clock with your womb clock, according to Dr Knight.

The failure to synchronise switches off body clock genes in cells lining the womb, which in turn, may jeopardise the pregnancy.

We know that approximately one in four to one in seven clinical pregnancies result in miscarriage, mostly prior to 12 weeks of pregnancy. It is estimated that five percent of women experience two clinical miscarriages and approximately one percent have three or more losses. From a medical perspective, recurrent miscarriages and implantation failure have remained frustrating because of the lack of any effective treatments.

We have some insight into why some women cannot bring pregnancies to full term, and it shows that the womb has a body clock of its own, and that this clock needs to synchronise with the mother's. Recently some womb biopsies were obtained from women who have experienced recurrent pregnancy loss.

Demeter Fertility Medical Director, Dr David Knight has over 15 years of Fertility experience. Demeter Fertility Medical Director, Dr David Knight has over 15 years of fertility experience

The cells from these biopsies were purified and then treated to simulate a pregnancy. A failure of embryonic and maternal body clock genes to synchronise caused quite catastrophic consequences.

Not only could this cause miscarriage or infertility, but more subtle synchronisation defects could increase the risk of complications in the later stages of pregnancy, such as pre-eclampsia, fetal growth restriction and pre-term birth. This also provides new insights into the known link between shift or night work and reproductive problems.

This information has helped the Dr Jessup and I, here at Demeter Fertility, develop strategies to optimise the fetal environment in the womb and to help more women have children. We would love to see you and help with this, so if you would like to know more, make an appointment to see one us at Hurstville or Liverpool.

Dr David Knight

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