Blog

Getting the right egg: Mild Ovarian Stimulation most effective IVF treatment for achieving pregnancy

There are a number of IVF protocols used by fertility specialists, each with their own pros and cons. Fertility treatment is a balance between success and patient discomfort; complications and cost. Mild Ovarian Stimulation (MOS), pioneered in Australia by Demeter Fertility’s Medical Director Dr David Knight offers patients a simpler ovarian stimulation protocol aimed at retrieving fewer oocytes (eggs) but of higher quality, thus producing better embryos and chances of pregnancy.


There are a number of IVF protocols used by fertility specialists, each with their own pros and cons. Fertility treatment is a balance between success and patient discomfort; complications and cost. Mild Ovarian Stimulation (MOS), pioneered in Australia by Demeter Fertility’s Medical Director Dr David Knight offers patients a simpler ovarian stimulation protocol aimed at retrieving fewer oocytes (eggs) but of higher quality, thus producing better embryos and chances of pregnancy.


MOS is often overlooked as it can be more difficult and less convenient for doctors and IVF clinics, yet it is much more tolerable for patients. The use of MOS means fewer side effects during treatment as a result of injections and medications, less eggs, less embryos and yet the same number of babies. It is a newer fertility treatment that was brought over to Australia by Dr Knight who studied and practiced MOS overseas in the US.

What is MOS? MOS can be defined as the administration of low doses and fewer days of FSH injections and GnRH antagonist co-treated cycles for ovarian stimulation in women undergoing IVF, aiming to limit the number of eggs collected to eight or less.

Commonly used IVF protocols including the Long Down Regulation are more complex, time consuming and often expensive for patients, and may also give rise to considerable patient discomfort due to the drawn out period of hormone injections, while increasing the chance of complications.

MOS benefits the patient as IVF costs are also reduced due to improved overall health economics of mild IVF treatment. When MOS is combined with a single embryo transfer policy, costs associated with pregnancy complications are dramatically decreased in most cases.

This IVF technique reduces the need for women to take powerful drugs while trying to fall pregnant, which helps overall physical and emotional health, as well as producing higher quality eggs. Patients are not required to get blood tests when undergoing MOS, which saves time, money, travel and alleviates stress for patients during what can be a challenging and stressful time.
“We prefer MOS for our patients, as the women undergoing treatment can avoid drawn out periods of hormone injections and blood tests, and we only need one single ultrasound to check on their process,” explains Dr Knight.

“MOS also only requires 7-8 days of drug treatment as opposed to 40 days, but still with the same success rate as traditional treatments.”

Book An Appointment
Ask A Question
Request More Information

Call 1300 899 850 or
Send an Enquiry