Specialty Fertility Treatments in Sydney
Specialty fertility treatments are for patients whose situation does not fit a standard IVF pathway, whether because of low AMH, age, repeated implantation failure or a poor response to previous stimulation. At Demeter Fertility that includes ovarian rejuvenation using platelet rich plasma, our Over 40s Fertility Program, personalised low AMH protocols, DuoStim double stimulation, recurrent implantation failure investigation, immune therapy, MTHFR support and integrated naturopathy and acupuncture. Many of our patients arrive after being turned away by another clinic, or after being told that donor eggs are their only remaining option. We have no age limit and no BMI restriction, we performed Australia’s first intraovarian PRP procedure in 2017, and every plan starts with a comprehensive assessment and an honest view of your prospects before you commit to anything.
What are specialty fertility treatments?
Standard IVF works well for a large proportion of patients. These treatments exist for everyone else. They are the protocols, procedures and diagnostics used when the standard pathway has not worked, or is unlikely to work first time.
The common thread is investigation before treatment. Repeating the same IVF cycle and hoping for a different outcome is not a strategy. We find out what is actually happening first, then choose the treatment that addresses it.


Ovarian Rejuvenation
Demeter Fertility performed the first intraovarian PRP procedure in Australia in 2017 and Dr. Knight has completed hundreds since. Platelet rich plasma, prepared from your own blood, is injected into the ovaries under ultrasound guidance to support follicle development. A 2024 systematic review of 38 studies reported significant improvements in the fertility parameters of women with diminished ovarian reserve. It is an emerging treatment and suitability is assessed individually.
IVF for women over 40
Egg quantity and quality both decline with age, and after 40 the margin for error narrows. That does not justify the age cut offs some clinics apply. Our program combines early diagnostics, protocols selected for lower responders, ovarian rejuvenation where appropriate, DuoStim where time is short and PGT testing where your medical history suggests it would be necessary. We accept patients other clinics have declined.
Explore the Over 40s Fertility Program or read the facts on fertility after 40


Treating low AMH and diminished ovarian reserve
Age is a key factor in fertility. While it’s well known that egg quantity and quality decline with age, becoming pregnant in your 40s is still possible – especially with the right medical support.
Our clinic offers advanced protocols, thorough diagnostics and ovarian rejuvenation to improve outcomes for women over 40 seeking IVF.
We also offer early and detailed fertility assessments, so we can tailor your IVF treatment plan from the very beginning.
Recurrent implantation failure (RIF) support
Repeated failed transfers, particularly when you have been told that everything looks fine, are among the most investigable problems in fertility treatment. Our work includes endometrial receptivity analysis, immune testing, hysteroscopy, clotting investigation and a review of modifiable factors, so that a cause can be identified and targeted.
Read about recurrent implantation failure and its causes


DuoStim double stimulation
Two stimulation phases and two egg collections within a single menstrual cycle, using both the follicular and luteal phases. For patients with low ovarian reserve or limited time, it accumulates embryos faster than waiting a full cycle between attempts.
Other specialty treatments
- Immune therapy for immune factors contributing to implantation failure or recurrent miscarriage
- MTHFR support for patients with gene variants affecting folate metabolism
- PGT testing to identify chromosomally normal embryos before transfer
- Natural and mild IVF for lower intervention protocols
- Naturopathy and acupuncture with in house practitioners rather than a referral elsewhere

Second opinions and complex fertility cases in Sydney
Many of our patients come to us after treatment elsewhere. Some have had several unsuccessful cycles. Some have been told they are too old, that their AMH is too low, or that their BMI disqualifies them. Changing clinics is straightforward, your records transfer, and a second opinion costs you a consultation rather than another full cycle. Read about changing IVF clinics
Why choose Demeter Fertility?

One of Australia’s most experienced teams in advanced IVF treatment, at the clinic that introduced intraovarian PRP to this country

Compassionate, science-led care tailored to your personal fertility story

Access to leading fertility diagnostics, personalised protocols and second opinion services

Transparent communication and consistent support throughout your journey

Four Sydney locations plus telehealth for interstate and international patients

No age limit and no BMI restriction

Winner, Most Trusted Family Owned Fertility Clinic 2024, NSW Healthcare and Pharmaceutical Awards

Family owned, so decisions are made clinically rather than by a corporate protocol
Start with clarity about where you stand
Whether you are beginning IVF, dealing with a low AMH result, exploring ovarian rejuvenation or looking for answers after failed cycles, the first step is the same: a comprehensive assessment and an honest conversation about your realistic options.
Hurstville: Suite 901, Level 9, Hurstville Plaza One, 288 Forest Rd, Hurstville NSW 2220. Phone 1300 899 850
Liverpool: Level 2/13 to 15 Moore St, Liverpool NSW 2170. Phone 1300 899 850
Westmead: Suite 9, Westmead Private Hospital, Cnr Darcy and Mons Road, Westmead NSW 2145. Phone (02) 9633 1349
Wahroonga: 212/185 Fox Valley Rd, Wahroonga NSW 2076. Phone (02) 9598 0211
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FAQs Specialty Fertility Treatments in Sydney
What are specialty fertility treatments?
Specialty fertility treatments are protocols and procedures used when standard IVF is not appropriate or has not worked. They include ovarian rejuvenation, tailored low AMH stimulation protocols, DuoStim double stimulation, recurrent implantation failure investigation, immune therapy and PGT testing.
What is advanced IVF treatment?
Advanced IVF treatment refers to the diagnostics and protocols used for complex cases, including patients with diminished ovarian reserve, patients over 40, poor responders and those with repeated implantation failure. It typically involves more investigation before treatment and a protocol built around the individual rather than a standard template.
Do you treat patients other clinics have declined?
Yes. Demeter Fertility has no age limit and no BMI restriction, and a significant proportion of our patients come to us after being declined or discharged elsewhere. We assess every patient individually.
Can I get a second opinion on my IVF treatment in Sydney?
Yes. Second opinions are one of the most common reasons patients contact us. We will review your history and previous cycles and give you our honest view, whether or not that means recommending treatment with us.
Which specialty treatments does Demeter offer that other clinics do not?
Ovarian rejuvenation using intraovarian PRP is the clearest example, having been introduced to Australia at Demeter Fertility in 2017. DuoStim double stimulation and our dedicated Over 40s Fertility Program are also offered by relatively few Australian clinics.
How do I know which specialty fertility treatment is right for me?
Through a comprehensive assessment. Your specialist reviews your history, previous cycles and current test results before recommending anything. There is no single treatment that suits every complex case.
Are specialty fertility treatments more expensive?
Costs vary depending on the treatments involved and what Medicare rebates apply to the IVF component. We provide an individual quote after your assessment.
Where are your Sydney clinics located?
Demeter Fertility consults at Hurstville, Wahroonga, Liverpool and Westmead. Initial consultations are available by telehealth for interstate and New Zealand patients.
Disclaimer
All information is general and not intended as a substitute for professional advice. Any surgical or invasive procedure carries risks.
